FAM83D-SF3B3 Fusion FISH Probe
The FAM83D-SF3B3 Fusion FISH Probe is used to confirm a fusion of the FAM83D and SF3B3 genes. The fusion of the FAM83D and SF3B3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM83D-SF3B3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-RERE | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-REOR | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-REGO | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-REGR | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-OROR | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-GORE | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-GROR | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM83D-SF3B3-20-AQAQ | 20 (40 μL) | 200 μL |
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SF3B3 Gene Summary
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]
Gene Name: Splicing Factor 3b Subunit 3
Chromosome: CHR16: 70557690 -70611571
Locus: 16q22.1
FAM83D Gene Summary
The Family With Sequence Similarity 83 Member D (FAM83D) gene is located on chr20 :37554954-37581703 at 20q11.23.
Gene Name: Family With Sequence Similarity 83 Member D
Chromosome: CHR20: 37554954 -37581703
Locus: 20q11.23
Gene Diseases
The FAM83D SF3B3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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