FAM60A-CD27 Fusion FISH Probe
The FAM60A-CD27 Fusion FISH Probe is used to confirm a fusion of the FAM60A and CD27 genes. The fusion of the FAM60A and CD27 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM60A-CD27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-RERE | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-REOR | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-REGO | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-REGR | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-OROR | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-GORE | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-GROR | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM60A-CD27-20-AQAQ | 20 (40 μL) | 200 μL |
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CD27 Gene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
Gene Name: CD27 Molecule
Chromosome: CHR12: 6554050 -6560884
Locus: 12p13.31
Gene Diseases
The FAM60A CD27 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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