FAM53B-KCNN1 Fusion FISH Probe
The FAM53B-KCNN1 Fusion FISH Probe is used to confirm a fusion of the FAM53B and KCNN1 genes. The fusion of the FAM53B and KCNN1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM53B-KCNN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-RERE | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-REOR | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-REGO | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-REGR | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-OROR | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-GORE | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-GROR | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM53B-KCNN1-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNN1 Gene Summary
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Calcium-activated Channel Subfamily N Member 1
Chromosome: CHR19: 18062110 -18109930
Locus: 19p13.11
FAM53B Gene Summary
The Family With Sequence Similarity 53 Member B (FAM53B) gene is located on chr10 :126307862-126432930 at 10q26.13.
Gene Name: Family With Sequence Similarity 53 Member B
Chromosome: CHR10: 126307862 -126432930
Locus: 10q26.13
Gene Diseases
The FAM53B KCNN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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