FAM49B-MRPL13 Fusion FISH Probe
The FAM49B-MRPL13 Fusion FISH Probe is used to confirm a fusion of the FAM49B and MRPL13 genes. The fusion of the FAM49B and MRPL13 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FAM49B-MRPL13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-RERE | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-REOR | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-REGR | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-OROR | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| FAM49B-MRPL13-20-AQAQ | 20 (40 μL) | 200 μL |
|
MRPL13 Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]
Gene Name: Mitochondrial Ribosomal Protein L13
Chromosome: CHR8: 121408082 -121457647
Locus: 8q24.12
FAM49B Gene Summary
The Family With Sequence Similarity 49 Member B (FAM49B) gene is located on chr8 :130853715-130952000 at 8q24.21.
Gene Name: Family With Sequence Similarity 49 Member B
Chromosome: CHR8: 130853715 -130952000
Locus: 8q24.21
Gene Diseases
The FAM49B MRPL13 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|