FAM38A-CBFA2T3 Fusion FISH Probe
The FAM38A-CBFA2T3 Fusion FISH Probe is used to confirm a fusion of the FAM38A and CBFA2T3 genes. The fusion of the FAM38A and CBFA2T3 genes has been associated with Ovarian Serous Cystadenocarcinoma, Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma, Esophageal Carcinoma, and Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM38A-CBFA2T3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-RERE | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-REOR | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-REGO | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-REGR | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-OROR | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-GORE | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-GROR | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM38A-CBFA2T3-20-AQAQ | 20 (40 μL) | 200 μL |
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CBFA2T3 Gene Summary
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
Gene Name: CBFA2/RUNX1 Translocation Partner 3
Chromosome: CHR16: 88941262 -89043504
Locus: 16q24.3
Gene Diseases
The FAM38A CBFA2T3 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
| Esophageal Carcinoma |
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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