FAM200A-CYP3A5 Fusion FISH Probe
The FAM200A-CYP3A5 Fusion FISH Probe is used to confirm a fusion of the FAM200A and CYP3A5 genes. The fusion of the FAM200A and CYP3A5 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM200A-CYP3A5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-RERE | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-REOR | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-REGO | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-REGR | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-OROR | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-GORE | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-GROR | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM200A-CYP3A5-20-AQAQ | 20 (40 μL) | 200 μL |
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CYP3A5 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Name: Cytochrome P450 Family 3 Subfamily A Member 5
Chromosome: CHR7: 99245812 -99277621
Locus: 7q22.1
FAM200A Gene Summary
This gene encodes a protein of unknown function. The protein is weakly similar to transposase-like proteins in human and mouse. [provided by RefSeq, Jul 2008]
Gene Name: Family With Sequence Similarity 200 Member A
Chromosome: CHR7: 99143922 -99149757
Locus: 7q22.1
Gene Diseases
The FAM200A CYP3A5 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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