FAM19A4-CACNA2D3 Fusion FISH Probe
The FAM19A4-CACNA2D3 Fusion FISH Probe is used to confirm a fusion of the FAM19A4 and CACNA2D3 genes. The fusion of the FAM19A4 and CACNA2D3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM19A4-CACNA2D3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-RERE | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-REOR | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-REGO | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-REGR | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-OROR | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-GORE | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-GROR | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM19A4-CACNA2D3-20-AQAQ | 20 (40 μL) | 200 μL |
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CACNA2D3 Gene Summary
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Gene Name: Calcium Voltage-gated Channel Auxiliary Subunit Alpha2delta 3
Chromosome: CHR3: 54156692 -55108584
Locus: 3p21.1-p14.3
FAM19A4 Gene Summary
This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011]
Gene Name: Family With Sequence Similarity 19 Member A4, C-C Motif Chemokine Like
Chromosome: CHR3: 68780916 -68981711
Locus: 3p14.1
Gene Diseases
The FAM19A4 CACNA2D3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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