FAM19A2-KCNMB4 Fusion FISH Probe
The FAM19A2-KCNMB4 Fusion FISH Probe is used to confirm a fusion of the FAM19A2 and KCNMB4 genes. The fusion of the FAM19A2 and KCNMB4 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM19A2-KCNMB4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-RERE | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-REOR | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-REGO | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-REGR | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-OROR | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-GORE | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-GROR | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM19A2-KCNMB4-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNMB4 Gene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Calcium-activated Channel Subfamily M Regulatory Beta Subunit 4
Chromosome: CHR12: 70760061 -70828072
Locus: 12q15
FAM19A2 Gene Summary
This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]
Gene Name: Family With Sequence Similarity 19 Member A2, C-C Motif Chemokine Like
Chromosome: CHR12: 62102040 -62586551
Locus: 12q14.1
Gene Diseases
The FAM19A2 KCNMB4 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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