FAM189A1-GABRG3 Fusion FISH Probe
The FAM189A1-GABRG3 Fusion FISH Probe is used to confirm a fusion of the FAM189A1 and GABRG3 genes. The fusion of the FAM189A1 and GABRG3 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM189A1-GABRG3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-RERE | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-REOR | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-REGO | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-REGR | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-OROR | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-GORE | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-GROR | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM189A1-GABRG3-20-AQAQ | 20 (40 μL) | 200 μL |
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GABRG3 Gene Summary
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
Gene Name: Gamma-aminobutyric Acid Type A Receptor Gamma3 Subunit
Chromosome: CHR15: 27216428 -27778373
Locus: 15q12
FAM189A1 Gene Summary
The Family With Sequence Similarity 189 Member A1 (FAM189A1) gene is located on chr15 :29412454-29862927 at 15q13.1.
Gene Name: Family With Sequence Similarity 189 Member A1
Chromosome: CHR15: 29412454 -29862927
Locus: 15q13.1
Gene Diseases
The FAM189A1 GABRG3 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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