FAM172A-FHIT Fusion FISH Probe
The FAM172A-FHIT Fusion FISH Probe is used to confirm a fusion of the FAM172A and FHIT genes. The fusion of the FAM172A and FHIT genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM172A-FHIT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-RERE | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-REOR | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-REGO | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-REGR | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-OROR | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-GORE | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-GROR | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM172A-FHIT-20-AQAQ | 20 (40 μL) | 200 μL |
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FHIT Gene Summary
The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]
Gene Name: Fragile Histidine Triad
Chromosome: CHR3: 59735035 -61237133
Locus: 3p14.2
FAM172A Gene Summary
The Family With Sequence Similarity 172 Member A (FAM172A) gene is located on chr5 :92953430-93447404 at 5q15.
Gene Name: Family With Sequence Similarity 172 Member A
Chromosome: CHR5: 92953430 -93447404
Locus: 5q15
Gene Diseases
The FAM172A FHIT Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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