FAM129A-NRXN2 Fusion FISH Probe
The FAM129A-NRXN2 Fusion FISH Probe is used to confirm a fusion of the FAM129A and NRXN2 genes. The fusion of the FAM129A and NRXN2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM129A-NRXN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-RERE | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-REOR | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-REGO | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-REGR | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-OROR | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-GORE | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-GROR | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM129A-NRXN2-20-AQAQ | 20 (40 μL) | 200 μL |
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NRXN2 Gene Summary
This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).[provided by RefSeq, Jun 2010]
Gene Name: Neurexin 2
Chromosome: CHR11: 64373645 -64490660
Locus: 11q13.1
FAM129A Gene Summary
This gene encodes a member of the family with sequence similarity 129 protein family. This gene is highly expressed in several cancer cells and may serve as a prognostic marker for certain cancers. The encoded protein may play a role in regulating p53-mediated apoptosis. [provided by RefSeq, Sep 2016]
Gene Name: Family With Sequence Similarity 129 Member A
Chromosome: CHR1: 184760165 -184943682
Locus: 1q25.3
Gene Diseases
The FAM129A NRXN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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