FAM125B-TG Fusion FISH Probe
The FAM125B-TG Fusion FISH Probe is used to confirm a fusion of the FAM125B and TG genes. The fusion of the FAM125B and TG genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM125B-TG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-RERE | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-REOR | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-REGO | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-REGR | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-OROR | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-GORE | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-GROR | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM125B-TG-20-AQAQ | 20 (40 μL) | 200 μL |
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TG Gene Summary
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
Gene Name: Thyroglobulin
Chromosome: CHR8: 133879204 -134147143
Locus: 8q24.22
Gene Diseases
The FAM125B TG Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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