FAM100B-TIMP2 Fusion FISH Probe
The FAM100B-TIMP2 Fusion FISH Probe is used to confirm a fusion of the FAM100B and TIMP2 genes. The fusion of the FAM100B and TIMP2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM100B-TIMP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-RERE | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-REOR | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-REGO | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-REGR | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-OROR | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-GORE | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-GROR | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM100B-TIMP2-20-AQAQ | 20 (40 μL) | 200 μL |
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TIMP2 Gene Summary
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
Gene Name: TIMP Metallopeptidase Inhibitor 2
Chromosome: CHR17: 76849058 -76921472
Locus: 17q25.3
Gene Diseases
The FAM100B TIMP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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