FAF1-TESK2 Fusion FISH Probe
The FAF1-TESK2 Fusion FISH Probe is used to confirm a fusion of the FAF1 and TESK2 genes. The fusion of the FAF1 and TESK2 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FAF1-TESK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| FAF1-TESK2-20-AQAQ | 20 (40 μL) | 200 μL |
|
TESK2 Gene Summary
This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: Testis-specific Kinase 2
Chromosome: CHR1: 45809554 -45956840
Locus: 1p34.1
FAF1 Gene Summary
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008]
Gene Name: Fas Associated Factor 1
Chromosome: CHR1: 50906934 -51425936
Locus: 1p32.3
Gene Diseases
The FAF1 TESK2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|