FAF1-ITGB3BP Fusion FISH Probe
The FAF1-ITGB3BP Fusion FISH Probe is used to confirm a fusion of the FAF1 and ITGB3BP genes. The fusion of the FAF1 and ITGB3BP genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAF1-ITGB3BP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-RERE | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-REOR | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-REGO | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-REGR | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-REAQ | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-ORRE | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-OROR | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-ORGO | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-GORE | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-GOOR | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-GOGO | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-GOGR | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-GRRE | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-GROR | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-GRGO | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-GRGR | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-AQRE | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-AQOR | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-AQGO | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-AQGR | 20 (40 μL) | 200 μL |
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| FAF1-ITGB3BP-20-AQAQ | 20 (40 μL) | 200 μL |
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FAF1 Gene Summary
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008]
Gene Name: Fas Associated Factor 1
Chromosome: CHR1: 50906934 -51425936
Locus: 1p32.3
ITGB3BP Gene Summary
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Gene Name: Integrin Subunit Beta 3 Binding Protein
Chromosome: CHR1: 63906440 -63988944
Locus: 1p31.3
Gene Diseases
The FAF1 ITGB3BP Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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