FAF1-DCAF6 Fusion FISH Probe
The FAF1-DCAF6 Fusion FISH Probe is used to confirm a fusion of the FAF1 and DCAF6 genes. The fusion of the FAF1 and DCAF6 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAF1-DCAF6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-RERE | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-REOR | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-REGO | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-REGR | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-REAQ | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-ORRE | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-OROR | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-ORGO | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-GORE | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-GOOR | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-GOGO | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-GOGR | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-GRRE | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-GROR | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-GRGO | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-GRGR | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-AQRE | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-AQOR | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-AQGO | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-AQGR | 20 (40 μL) | 200 μL |
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| FAF1-DCAF6-20-AQAQ | 20 (40 μL) | 200 μL |
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FAF1 Gene Summary
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008]
Gene Name: Fas Associated Factor 1
Chromosome: CHR1: 50906934 -51425936
Locus: 1p32.3
DCAF6 Gene Summary
The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression. [provided by RefSeq, Mar 2017]
Gene Name: DDB1 And CUL4 Associated Factor 6
Chromosome: CHR1: 167905796 -168045083
Locus: 1q24.2
Gene Diseases
The FAF1 DCAF6 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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