F5-SCYL3 Fusion FISH Probe
The F5-SCYL3 Fusion FISH Probe is used to confirm a fusion of the F5 and SCYL3 genes. The fusion of the F5 and SCYL3 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| F5-SCYL3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-RERE | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-REOR | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-REGO | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-REGR | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-REAQ | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-ORRE | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-OROR | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-ORGO | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-ORAQ | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-GORE | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-GOOR | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-GOGO | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-GOGR | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-GOAQ | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-GRRE | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-GROR | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-GRGO | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-GRGR | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-GRAQ | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-AQRE | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-AQOR | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-AQGO | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-AQGR | 20 (40 μL) | 200 μL |
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| F5-SCYL3-20-AQAQ | 20 (40 μL) | 200 μL |
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F5 Gene Summary
This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. [provided by RefSeq, Oct 2008]
Gene Name: Coagulation Factor V
Chromosome: CHR1: 169481191 -169555769
Locus: 1q24.2
SCYL3 Gene Summary
This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C-terminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012]
Gene Name: SCY1 Like Pseudokinase 3
Chromosome: CHR1: 169821803 -169863076
Locus: 1q24.2
Gene Diseases
The F5 SCYL3 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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