F11R-USF1 Fusion FISH Probe
The F11R-USF1 Fusion FISH Probe is used to confirm a fusion of the F11R and USF1 genes. The fusion of the F11R and USF1 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| F11R-USF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-RERE | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-REOR | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-REGO | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-REGR | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-REAQ | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-ORRE | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-OROR | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-ORGO | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-GORE | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-GOOR | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-GOGO | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-GOGR | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-GRRE | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-GROR | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-GRGO | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-GRGR | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-AQRE | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-AQOR | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-AQGO | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-AQGR | 20 (40 μL) | 200 μL |
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| F11R-USF1-20-AQAQ | 20 (40 μL) | 200 μL |
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USF1 Gene Summary
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21. [provided by RefSeq, Feb 2013]
Gene Name: Upstream Transcription Factor 1
Chromosome: CHR1: 161009040 -161015757
Locus: 1q23.3
F11R Gene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
Gene Name: F11 Receptor
Chromosome: CHR1: 160965000 -160991133
Locus: 1q23.3
Gene Diseases
The F11R USF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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