EZR-ROS1 Fusion FISH Probe
The EZR-ROS1 Fusion FISH Probe is used to confirm a fusion of the EZR and ROS1 genes. The fusion of the EZR and ROS1 genes has been associated with Lung Adenocarcinoma, and Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EZR-ROS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-RERE | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-REOR | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-REGO | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-REGR | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-REAQ | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-ORRE | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-OROR | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-ORGO | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-GORE | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-GOOR | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-GOGO | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-GOGR | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-GRRE | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-GROR | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-GRGO | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-GRGR | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-AQRE | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-AQOR | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-AQGO | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-AQGR | 20 (40 μL) | 200 μL |
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| EZR-ROS1-20-AQAQ | 20 (40 μL) | 200 μL |
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ROS1 Gene Summary
This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]
Gene Name: ROS Proto-oncogene 1, Receptor Tyrosine Kinase
Chromosome: CHR6: 117609529 -117747018
Locus: 6q22.1
EZR Gene Summary
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Ezrin
Chromosome: CHR6: 159186772 -159240456
Locus: 6q25.3
Gene Diseases
The EZR ROS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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