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EZH1-MAP3K14 Fusion FISH Probe

The EZH1-MAP3K14 Fusion FISH Probe is used to confirm a fusion of the EZH1 and MAP3K14 genes. The fusion of the EZH1 and MAP3K14 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
EZH1-MAP3K14-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
EZH1-MAP3K14-20-RERE 20 (40 μL) 200 μL
EZH1-MAP3K14-20-REOR 20 (40 μL) 200 μL
EZH1-MAP3K14-20-REGO 20 (40 μL) 200 μL
EZH1-MAP3K14-20-REGR 20 (40 μL) 200 μL
EZH1-MAP3K14-20-REAQ 20 (40 μL) 200 μL
EZH1-MAP3K14-20-ORRE 20 (40 μL) 200 μL
EZH1-MAP3K14-20-OROR 20 (40 μL) 200 μL
EZH1-MAP3K14-20-ORGO 20 (40 μL) 200 μL
EZH1-MAP3K14-20-ORAQ 20 (40 μL) 200 μL
EZH1-MAP3K14-20-GORE 20 (40 μL) 200 μL
EZH1-MAP3K14-20-GOOR 20 (40 μL) 200 μL
EZH1-MAP3K14-20-GOGO 20 (40 μL) 200 μL
EZH1-MAP3K14-20-GOGR 20 (40 μL) 200 μL
EZH1-MAP3K14-20-GOAQ 20 (40 μL) 200 μL
EZH1-MAP3K14-20-GRRE 20 (40 μL) 200 μL
EZH1-MAP3K14-20-GROR 20 (40 μL) 200 μL
EZH1-MAP3K14-20-GRGO 20 (40 μL) 200 μL
EZH1-MAP3K14-20-GRGR 20 (40 μL) 200 μL
EZH1-MAP3K14-20-GRAQ 20 (40 μL) 200 μL
EZH1-MAP3K14-20-AQRE 20 (40 μL) 200 μL
EZH1-MAP3K14-20-AQOR 20 (40 μL) 200 μL
EZH1-MAP3K14-20-AQGO 20 (40 μL) 200 μL
EZH1-MAP3K14-20-AQGR 20 (40 μL) 200 μL
EZH1-MAP3K14-20-AQAQ 20 (40 μL) 200 μL

EZH1 Gene Summary

EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).[supplied by OMIM, Mar 2009]

Gene Name: Enhancer Of Zeste 1 Polycomb Repressive Complex 2 Subunit

Chromosome: CHR17: 40852292 -40897071

Locus: 17q21.2

MAP3K14 Gene Summary

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]

Gene Name: Mitogen-activated Protein Kinase Kinase Kinase 14

Chromosome: CHR17: 43340487 -43394414

Locus: 17q21.31

Gene Diseases

The EZH1 MAP3K14 Fusion has been associated with the following diseases:

Disease Name
Ovarian Serous Cystadenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.