EYA3-GUCA1C Fusion FISH Probe
The EYA3-GUCA1C Fusion FISH Probe is used to confirm a fusion of the EYA3 and GUCA1C genes. The fusion of the EYA3 and GUCA1C genes has been associated with Lung Adenocarcinoma, and Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EYA3-GUCA1C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-RERE | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-REOR | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-REGO | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-REGR | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-REAQ | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-ORRE | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-OROR | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-ORGO | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-ORAQ | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-GORE | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-GOOR | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-GOGO | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-GOGR | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-GOAQ | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-GRRE | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-GROR | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-GRGO | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-GRGR | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-GRAQ | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-AQRE | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-AQOR | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-AQGO | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-AQGR | 20 (40 μL) | 200 μL |
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| EYA3-GUCA1C-20-AQAQ | 20 (40 μL) | 200 μL |
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EYA3 Gene Summary
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: EYA Transcriptional Coactivator And Phosphatase 3
Chromosome: CHR1: 28296854 -28415148
Locus: 1p35.3
GUCA1C Gene Summary
The Guanylate Cyclase Activator 1C (GUCA1C) gene is located on chr3 :108626641-108672677 at 3q13.13.
Gene Name: Guanylate Cyclase Activator 1C
Chromosome: CHR3: 108626641 -108672677
Locus: 3q13.13
Gene Diseases
The EYA3 GUCA1C Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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