SEARCH OUR PRODUCT CATALOG

EXT2-ALKBH3 Fusion FISH Probe

The EXT2-ALKBH3 Fusion FISH Probe is used to confirm a fusion of the EXT2 and ALKBH3 genes. The fusion of the EXT2 and ALKBH3 genes has been associated with Skin Cutaneous Melanoma, and Pheochromocytoma And Paraganglioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
EXT2-ALKBH3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
EXT2-ALKBH3-20-RERE 20 (40 μL) 200 μL
EXT2-ALKBH3-20-REOR 20 (40 μL) 200 μL
EXT2-ALKBH3-20-REGO 20 (40 μL) 200 μL
EXT2-ALKBH3-20-REGR 20 (40 μL) 200 μL
EXT2-ALKBH3-20-REAQ 20 (40 μL) 200 μL
EXT2-ALKBH3-20-ORRE 20 (40 μL) 200 μL
EXT2-ALKBH3-20-OROR 20 (40 μL) 200 μL
EXT2-ALKBH3-20-ORGO 20 (40 μL) 200 μL
EXT2-ALKBH3-20-ORAQ 20 (40 μL) 200 μL
EXT2-ALKBH3-20-GORE 20 (40 μL) 200 μL
EXT2-ALKBH3-20-GOOR 20 (40 μL) 200 μL
EXT2-ALKBH3-20-GOGO 20 (40 μL) 200 μL
EXT2-ALKBH3-20-GOGR 20 (40 μL) 200 μL
EXT2-ALKBH3-20-GOAQ 20 (40 μL) 200 μL
EXT2-ALKBH3-20-GRRE 20 (40 μL) 200 μL
EXT2-ALKBH3-20-GROR 20 (40 μL) 200 μL
EXT2-ALKBH3-20-GRGO 20 (40 μL) 200 μL
EXT2-ALKBH3-20-GRGR 20 (40 μL) 200 μL
EXT2-ALKBH3-20-GRAQ 20 (40 μL) 200 μL
EXT2-ALKBH3-20-AQRE 20 (40 μL) 200 μL
EXT2-ALKBH3-20-AQOR 20 (40 μL) 200 μL
EXT2-ALKBH3-20-AQGO 20 (40 μL) 200 μL
EXT2-ALKBH3-20-AQGR 20 (40 μL) 200 μL
EXT2-ALKBH3-20-AQAQ 20 (40 μL) 200 μL

EXT2 Gene Summary

This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Exostosin Glycosyltransferase 2

Chromosome: CHR11: 44117098 -44266980

Locus: 11p11.2

ALKBH3 Gene Summary

The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]

Gene Name: AlkB Homolog 3, Alpha-ketoglutaratedependent Dioxygenase

Chromosome: CHR11: 43902356 -43941825

Locus: 11p11.2

Gene Diseases

The EXT2 ALKBH3 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma
Pheochromocytoma And Paraganglioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.