EXOC6B-SLC4A5 Fusion FISH Probe
The EXOC6B-SLC4A5 Fusion FISH Probe is used to confirm a fusion of the EXOC6B and SLC4A5 genes. The fusion of the EXOC6B and SLC4A5 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EXOC6B-SLC4A5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-RERE | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-REOR | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-REGO | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-REGR | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-REAQ | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-ORRE | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-OROR | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-ORGO | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-ORAQ | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-GORE | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-GOOR | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-GOGO | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-GOGR | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-GOAQ | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-GRRE | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-GROR | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-GRGO | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-GRGR | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-GRAQ | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-AQRE | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-AQOR | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-AQGO | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-AQGR | 20 (40 μL) | 200 μL |
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| EXOC6B-SLC4A5-20-AQAQ | 20 (40 μL) | 200 μL |
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EXOC6B Gene Summary
This gene encodes a protein which is a part of the evolutionarily conserved exocyst, a multimeric protein complex necessary for exocytosis, which in turn, is crucial for cell growth, polarity and migration. Disruption of this gene may be associated with phenotypes exhibiting multiple symptoms including intellectual disability and developmental delay (DD). [provided by RefSeq, Jun 2016]
Gene Name: Exocyst Complex Component 6B
Chromosome: CHR2: 72406443 -73053177
Locus: 2p13.2
SLC4A5 Gene Summary
This gene encodes a member of the sodium bicarbonate cotransporter (NBC) family, part of the bicarbonate transporter superfamily. Sodium bicarbonate cotransporters are involved in intracellular pH regulation and electroneural or electrogenic sodium bicarbonate transport. This protein is thought to be an integral membrane protein. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Solute Carrier Family 4 Member 5
Chromosome: CHR2: 74443368 -74570534
Locus: 2p13.1
Gene Diseases
The EXOC6B SLC4A5 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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