EXOC4-SLC25A13 Fusion FISH Probe
The EXOC4-SLC25A13 Fusion FISH Probe is used to confirm a fusion of the EXOC4 and SLC25A13 genes. The fusion of the EXOC4 and SLC25A13 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EXOC4-SLC25A13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-RERE | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-REOR | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-REGO | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-REGR | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-REAQ | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-ORRE | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-OROR | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-ORGO | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-ORAQ | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-GORE | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-GOOR | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-GOGO | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-GOGR | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-GOAQ | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-GRRE | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-GROR | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-GRGO | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-GRGR | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-GRAQ | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-AQRE | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-AQOR | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-AQGO | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-AQGR | 20 (40 μL) | 200 μL |
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| EXOC4-SLC25A13-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC25A13 Gene Summary
This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Name: Solute Carrier Family 25 Member 13
Chromosome: CHR7: 95749531 -95951459
Locus: 7q21.3
EXOC4 Gene Summary
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Exocyst Complex Component 4
Chromosome: CHR7: 132937822 -133750513
Locus: 7q33
Gene Diseases
The EXOC4 SLC25A13 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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