EXOC1-XKR3 Fusion FISH Probe
The EXOC1-XKR3 Fusion FISH Probe is used to confirm a fusion of the EXOC1 and XKR3 genes. The fusion of the EXOC1 and XKR3 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EXOC1-XKR3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| EXOC1-XKR3-20-AQAQ | 20 (40 μL) | 200 μL |
|
EXOC1 Gene Summary
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Exocyst Complex Component 1
Chromosome: CHR4: 56719815 -56771244
Locus: 4q12
XKR3 Gene Summary
XKRX (MIM 300684) and XKR3 are homologs of the Kell blood group precursor XK (MIM 314850), which is a putative membrane transporter and a component of the XK/Kell complex of the Kell blood group system (Calenda et al., 2006 [PubMed 16431037]).[supplied by OMIM, Mar 2008]
Gene Name: XK Related 3
Chromosome: CHR22: 17264305 -17302584
Locus: 22q11.1
Gene Diseases
The EXOC1 XKR3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|