EVI5L-PGPEP1 Fusion FISH Probe
The EVI5L-PGPEP1 Fusion FISH Probe is used to confirm a fusion of the EVI5L and PGPEP1 genes. The fusion of the EVI5L and PGPEP1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EVI5L-PGPEP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-RERE | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-REOR | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-REGO | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-REGR | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-REAQ | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-ORRE | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-OROR | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-ORGO | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-GORE | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-GOOR | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-GOGO | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-GOGR | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-GRRE | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-GROR | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-GRGO | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-GRGR | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-AQRE | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-AQOR | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-AQGO | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-AQGR | 20 (40 μL) | 200 μL |
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| EVI5L-PGPEP1-20-AQAQ | 20 (40 μL) | 200 μL |
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PGPEP1 Gene Summary
The gene encodes a cysteine protease and member of the peptidase C15 family of proteins. The encoded protein cleaves amino terminal pyroglutamate residues from protein substrates including thyrotropin-releasing hormone and other neuropeptides. Expression of this gene may be downregulated in colorectal cancer, while activity of the encoded protein may be negatively correlated with cancer progression in colorectal cancer patients. Activity of the encoded protease may also be altered in other disease states including in liver cirrhosis, which is associated with reduced protease activity, and in necrozoospermia, which is associated with elevated protease activity. [provided by RefSeq, Jul 2016]
Gene Name: Pyroglutamyl-peptidase I
Chromosome: CHR19: 18451407 -18480763
Locus: 19p13.11
EVI5L Gene Summary
The Ecotropic Viral Integration Site 5 Like (EVI5L) gene is located on chr19 :7895160-7929862 at 19p13.2.
Gene Name: Ecotropic Viral Integration Site 5 Like
Chromosome: CHR19: 7895160 -7929862
Locus: 19p13.2
Gene Diseases
The EVI5L PGPEP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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