ETV6-CIDEA Fusion FISH Probe
The ETV6-CIDEA Fusion FISH Probe is used to confirm a fusion of the ETV6 and CIDEA genes. The fusion of the ETV6 and CIDEA genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ETV6-CIDEA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-RERE | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-REOR | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-REGO | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-REGR | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-REAQ | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-ORRE | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-OROR | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-ORGO | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-ORAQ | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-GORE | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-GOOR | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-GOGO | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-GOGR | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-GOAQ | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-GRRE | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-GROR | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-GRGO | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-GRGR | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-GRAQ | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-AQRE | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-AQOR | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-AQGO | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-AQGR | 20 (40 μL) | 200 μL |
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| ETV6-CIDEA-20-AQAQ | 20 (40 μL) | 200 μL |
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CIDEA Gene Summary
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq, Aug 2010]
Gene Name: Cell Death-inducing DFFA-like Effector A
Chromosome: CHR18: 12254317 -12277594
Locus: 18
ETV6 Gene Summary
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008]
Gene Name: ETS Variant 6
Chromosome: CHR12: 11802787 -12048325
Locus: 12p13.2
Gene Diseases
The ETV6 CIDEA Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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