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ETV3-MNDA Fusion FISH Probe

The ETV3-MNDA Fusion FISH Probe is used to confirm a fusion of the ETV3 and MNDA genes. The fusion of the ETV3 and MNDA genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ETV3-MNDA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ETV3-MNDA-20-RERE 20 (40 μL) 200 μL
ETV3-MNDA-20-REOR 20 (40 μL) 200 μL
ETV3-MNDA-20-REGO 20 (40 μL) 200 μL
ETV3-MNDA-20-REGR 20 (40 μL) 200 μL
ETV3-MNDA-20-REAQ 20 (40 μL) 200 μL
ETV3-MNDA-20-ORRE 20 (40 μL) 200 μL
ETV3-MNDA-20-OROR 20 (40 μL) 200 μL
ETV3-MNDA-20-ORGO 20 (40 μL) 200 μL
ETV3-MNDA-20-ORAQ 20 (40 μL) 200 μL
ETV3-MNDA-20-GORE 20 (40 μL) 200 μL
ETV3-MNDA-20-GOOR 20 (40 μL) 200 μL
ETV3-MNDA-20-GOGO 20 (40 μL) 200 μL
ETV3-MNDA-20-GOGR 20 (40 μL) 200 μL
ETV3-MNDA-20-GOAQ 20 (40 μL) 200 μL
ETV3-MNDA-20-GRRE 20 (40 μL) 200 μL
ETV3-MNDA-20-GROR 20 (40 μL) 200 μL
ETV3-MNDA-20-GRGO 20 (40 μL) 200 μL
ETV3-MNDA-20-GRGR 20 (40 μL) 200 μL
ETV3-MNDA-20-GRAQ 20 (40 μL) 200 μL
ETV3-MNDA-20-AQRE 20 (40 μL) 200 μL
ETV3-MNDA-20-AQOR 20 (40 μL) 200 μL
ETV3-MNDA-20-AQGO 20 (40 μL) 200 μL
ETV3-MNDA-20-AQGR 20 (40 μL) 200 μL
ETV3-MNDA-20-AQAQ 20 (40 μL) 200 μL

ETV3 Gene Summary

The ETS Variant 3 (ETV3) gene is located on chr1 :157094458-157108383 at 1q23.1.

Gene Name: ETS Variant 3

Chromosome: CHR1: 157094458 -157108383

Locus: 1q23.1

MNDA Gene Summary

The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008]

Gene Name: Myeloid Cell Nuclear Differentiation Antigen

Chromosome: CHR1: 158801167 -158819270

Locus: 1q23.1

Gene Diseases

The ETV3 MNDA Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.