ESYT1-MED14 Fusion FISH Probe
The ESYT1-MED14 Fusion FISH Probe is used to confirm a fusion of the ESYT1 and MED14 genes. The fusion of the ESYT1 and MED14 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ESYT1-MED14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-RERE | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-REOR | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-REGO | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-REGR | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-REAQ | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-ORRE | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-OROR | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-ORGO | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-ORAQ | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-GORE | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-GOOR | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-GOGO | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-GOGR | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-GOAQ | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-GRRE | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-GROR | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-GRGO | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-GRGR | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-GRAQ | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-AQRE | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-AQOR | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-AQGO | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-AQGR | 20 (40 μL) | 200 μL |
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| ESYT1-MED14-20-AQAQ | 20 (40 μL) | 200 μL |
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MED14 Gene Summary
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq, Jul 2008]
Gene Name: Mediator Complex Subunit 14
Chromosome: CHRX: 40508794 -40594804
Locus: Xp11.4
ESYT1 Gene Summary
The Extended Synaptotagmin 1 (ESYT1) gene is located on chr12 :56521985-56538460 at 12q13.2.
Gene Name: Extended Synaptotagmin 1
Chromosome: CHR12: 56521985 -56538460
Locus: 12q13.2
Gene Diseases
The ESYT1 MED14 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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