ESCO1-CPNE1 Fusion FISH Probe
The ESCO1-CPNE1 Fusion FISH Probe is used to confirm a fusion of the ESCO1 and CPNE1 genes. The fusion of the ESCO1 and CPNE1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ESCO1-CPNE1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-RERE | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-REOR | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-REGO | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-REGR | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-REAQ | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-ORRE | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-OROR | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-ORGO | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-GORE | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-GOOR | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-GOGO | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-GOGR | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-GRRE | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-GROR | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-GRGO | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-GRGR | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-AQRE | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-AQOR | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-AQGO | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-AQGR | 20 (40 μL) | 200 μL |
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| ESCO1-CPNE1-20-AQAQ | 20 (40 μL) | 200 μL |
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CPNE1 Gene Summary
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Aug 2008]
Gene Name: Copine 1
Chromosome: CHR20: 34213952 -34252878
Locus: 20q11.22
ESCO1 Gene Summary
ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion (Hou and Zou, 2005 [PubMed 15958495]).[supplied by OMIM, Mar 2008]
Gene Name: Establishment Of Sister Chromatid Cohesion N-acetyltransferase 1
Chromosome: CHR18: 19109261 -19180693
Locus: 18q11.2
Gene Diseases
The ESCO1 CPNE1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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