ERRFI1-NCF2 Fusion FISH Probe
The ERRFI1-NCF2 Fusion FISH Probe is used to confirm a fusion of the ERRFI1 and NCF2 genes. The fusion of the ERRFI1 and NCF2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ERRFI1-NCF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-RERE | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-REOR | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-REGO | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-REGR | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-REAQ | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-ORRE | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-OROR | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-ORGO | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-GORE | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-GOOR | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-GOGO | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-GOGR | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-GRRE | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-GROR | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-GRGO | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-GRGR | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-AQRE | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-AQOR | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-AQGO | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-AQGR | 20 (40 μL) | 200 μL |
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| ERRFI1-NCF2-20-AQAQ | 20 (40 μL) | 200 μL |
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NCF2 Gene Summary
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]
Gene Name: Neutrophil Cytosolic Factor 2
Chromosome: CHR1: 183524696 -183560056
Locus: 1q25.3
ERRFI1 Gene Summary
ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885]; Fiorentino et al., 2000 [PubMed 11003669]).[supplied by OMIM, Mar 2008]
Gene Name: ERBB Receptor Feedback Inhibitor 1
Chromosome: CHR1: 8071778 -8086393
Locus: 1p36.23
Gene Diseases
The ERRFI1 NCF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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