ERP44-CHRDL2 Fusion FISH Probe
The ERP44-CHRDL2 Fusion FISH Probe is used to confirm a fusion of the ERP44 and CHRDL2 genes. The fusion of the ERP44 and CHRDL2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ERP44-CHRDL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-RERE | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-REOR | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-REGO | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-REGR | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-REAQ | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-ORRE | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-OROR | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-ORGO | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-GORE | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-GOOR | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-GOGO | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-GOGR | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-GRRE | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-GROR | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-GRGO | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-GRGR | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-AQRE | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-AQOR | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-AQGO | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-AQGR | 20 (40 μL) | 200 μL |
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| ERP44-CHRDL2-20-AQAQ | 20 (40 μL) | 200 μL |
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ERP44 Gene Summary
This gene encodes a member of the protein disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins. It has an inferred N-terminal signal peptide, a catalytically active thioredoxin (TRX) domain, two TRX-like domains and a C-terminal ER-retention sequence. This protein functions as a pH-regulated chaperone of the secretory pathway and likely plays a role in protein quality control at the endoplasmic reticulum - Golgi interface. [provided by RefSeq, Dec 2016]
Gene Name: Endoplasmic Reticulum Protein 44
Chromosome: CHR9: 102741462 -102861330
Locus: 9q31.1
CHRDL2 Gene Summary
This gene encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration. [provided by RefSeq, Jan 2015]
Gene Name: Chordin Like 2
Chromosome: CHR11: 74407473 -74442186
Locus: 11q13.4
Gene Diseases
The ERP44 CHRDL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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