ERC1-VWF Fusion FISH Probe
The ERC1-VWF Fusion FISH Probe is used to confirm a fusion of the ERC1 and VWF genes. The fusion of the ERC1 and VWF genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ERC1-VWF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ERC1-VWF-20-AQAQ | 20 (40 μL) | 200 μL |
|
VWF Gene Summary
This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]
Gene Name: Von Willebrand Factor
Chromosome: CHR12: 6058039 -6233836
Locus: 12p13.31
ERC1 Gene Summary
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: ELKS/RAB6-interacting/CAST Family Member 1
Chromosome: CHR12: 1100403 -1605099
Locus: 12p13.33
Gene Diseases
The ERC1 VWF Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|