ERC1-MRPS9 Fusion FISH Probe
The ERC1-MRPS9 Fusion FISH Probe is used to confirm a fusion of the ERC1 and MRPS9 genes. The fusion of the ERC1 and MRPS9 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ERC1-MRPS9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-RERE | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-REOR | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-REGO | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-REGR | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-REAQ | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-ORRE | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-OROR | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-ORGO | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-ORAQ | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-GORE | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-GOOR | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-GOGO | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-GOGR | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-GOAQ | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-GRRE | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-GROR | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-GRGO | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-GRGR | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-GRAQ | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-AQRE | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-AQOR | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-AQGO | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-AQGR | 20 (40 μL) | 200 μL |
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| ERC1-MRPS9-20-AQAQ | 20 (40 μL) | 200 μL |
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ERC1 Gene Summary
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: ELKS/RAB6-interacting/CAST Family Member 1
Chromosome: CHR12: 1100403 -1605099
Locus: 12p13.33
MRPS9 Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. [provided by RefSeq, Jul 2008]
Gene Name: Mitochondrial Ribosomal Protein S9
Chromosome: CHR2: 105654482 -105716418
Locus: 2q12.1
Gene Diseases
The ERC1 MRPS9 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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