ERC1-GABRB1 Fusion FISH Probe
The ERC1-GABRB1 Fusion FISH Probe is used to confirm a fusion of the ERC1 and GABRB1 genes. The fusion of the ERC1 and GABRB1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ERC1-GABRB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-RERE | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-REOR | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-REGO | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-REGR | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-REAQ | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-ORRE | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-OROR | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-ORGO | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-GORE | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-GOOR | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-GOGO | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-GOGR | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-GRRE | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-GROR | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-GRGO | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-GRGR | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-AQRE | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-AQOR | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-AQGO | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-AQGR | 20 (40 μL) | 200 μL |
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| ERC1-GABRB1-20-AQAQ | 20 (40 μL) | 200 μL |
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GABRB1 Gene Summary
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008]
Gene Name: Gamma-aminobutyric Acid Type A Receptor Beta1 Subunit
Chromosome: CHR4: 47033294 -47428447
Locus: 4p12
ERC1 Gene Summary
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: ELKS/RAB6-interacting/CAST Family Member 1
Chromosome: CHR12: 1100403 -1605099
Locus: 12p13.33
Gene Diseases
The ERC1 GABRB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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