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EPHA3-ABCA9 Fusion FISH Probe

The EPHA3-ABCA9 Fusion FISH Probe is used to confirm a fusion of the EPHA3 and ABCA9 genes. The fusion of the EPHA3 and ABCA9 genes has been associated with Thymoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
EPHA3-ABCA9-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
EPHA3-ABCA9-20-RERE 20 (40 μL) 200 μL
EPHA3-ABCA9-20-REOR 20 (40 μL) 200 μL
EPHA3-ABCA9-20-REGO 20 (40 μL) 200 μL
EPHA3-ABCA9-20-REGR 20 (40 μL) 200 μL
EPHA3-ABCA9-20-REAQ 20 (40 μL) 200 μL
EPHA3-ABCA9-20-ORRE 20 (40 μL) 200 μL
EPHA3-ABCA9-20-OROR 20 (40 μL) 200 μL
EPHA3-ABCA9-20-ORGO 20 (40 μL) 200 μL
EPHA3-ABCA9-20-ORAQ 20 (40 μL) 200 μL
EPHA3-ABCA9-20-GORE 20 (40 μL) 200 μL
EPHA3-ABCA9-20-GOOR 20 (40 μL) 200 μL
EPHA3-ABCA9-20-GOGO 20 (40 μL) 200 μL
EPHA3-ABCA9-20-GOGR 20 (40 μL) 200 μL
EPHA3-ABCA9-20-GOAQ 20 (40 μL) 200 μL
EPHA3-ABCA9-20-GRRE 20 (40 μL) 200 μL
EPHA3-ABCA9-20-GROR 20 (40 μL) 200 μL
EPHA3-ABCA9-20-GRGO 20 (40 μL) 200 μL
EPHA3-ABCA9-20-GRGR 20 (40 μL) 200 μL
EPHA3-ABCA9-20-GRAQ 20 (40 μL) 200 μL
EPHA3-ABCA9-20-AQRE 20 (40 μL) 200 μL
EPHA3-ABCA9-20-AQOR 20 (40 μL) 200 μL
EPHA3-ABCA9-20-AQGO 20 (40 μL) 200 μL
EPHA3-ABCA9-20-AQGR 20 (40 μL) 200 μL
EPHA3-ABCA9-20-AQAQ 20 (40 μL) 200 μL

EPHA3 Gene Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

Gene Name: EPH Receptor A3

Chromosome: CHR3: 89156673 -89531284

Locus: 3p11.1

ABCA9 Gene Summary

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [provided by RefSeq, Jul 2008]

Gene Name: ATP Binding Cassette Subfamily A Member 9

Chromosome: CHR17: 66970772 -67057136

Locus: 17q24.2

Gene Diseases

The EPHA3 ABCA9 Fusion has been associated with the following diseases:

Disease Name
Thymoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.