EPHA10-COL8A2 Fusion FISH Probe
The EPHA10-COL8A2 Fusion FISH Probe is used to confirm a fusion of the EPHA10 and COL8A2 genes. The fusion of the EPHA10 and COL8A2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EPHA10-COL8A2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-RERE | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-REOR | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-REGO | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-REGR | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-REAQ | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-ORRE | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-OROR | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-ORGO | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-ORAQ | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-GORE | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-GOOR | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-GOGO | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-GOGR | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-GOAQ | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-GRRE | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-GROR | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-GRGO | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-GRGR | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-GRAQ | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-AQRE | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-AQOR | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-AQGO | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-AQGR | 20 (40 μL) | 200 μL |
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| EPHA10-COL8A2-20-AQAQ | 20 (40 μL) | 200 μL |
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COL8A2 Gene Summary
This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Gene Name: Collagen Type VIII Alpha 2 Chain
Chromosome: CHR1: 36560843 -36565850
Locus: 1p34.3
EPHA10 Gene Summary
Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008]
Gene Name: EPH Receptor A10
Chromosome: CHR1: 38181645 -38230824
Locus: 1p34.3
Gene Diseases
The EPHA10 COL8A2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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