EPB41L1-GHRH Fusion FISH Probe
The EPB41L1-GHRH Fusion FISH Probe is used to confirm a fusion of the EPB41L1 and GHRH genes. The fusion of the EPB41L1 and GHRH genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EPB41L1-GHRH-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-RERE | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-REOR | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-REGO | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-REGR | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-REAQ | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-ORRE | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-OROR | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-ORGO | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-ORAQ | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-GORE | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-GOOR | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-GOGO | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-GOGR | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-GOAQ | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-GRRE | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-GROR | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-GRGO | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-GRGR | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-GRAQ | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-AQRE | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-AQOR | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-AQGO | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-AQGR | 20 (40 μL) | 200 μL |
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| EPB41L1-GHRH-20-AQAQ | 20 (40 μL) | 200 μL |
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EPB41L1 Gene Summary
Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
Gene Name: Erythrocyte Membrane Protein Band 4.1 Like 1
Chromosome: CHR20: 34700347 -34820721
Locus: 20q11.23
GHRH Gene Summary
This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor, known as somatoliberin, which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Name: Growth Hormone Releasing Hormone
Chromosome: CHR20: 35879489 -35885299
Locus: 20q11.23
Gene Diseases
The EPB41L1 GHRH Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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