EPB41L1-BCL2A1 Fusion FISH Probe
The EPB41L1-BCL2A1 Fusion FISH Probe is used to confirm a fusion of the EPB41L1 and BCL2A1 genes. The fusion of the EPB41L1 and BCL2A1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EPB41L1-BCL2A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-RERE | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-REOR | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-REGO | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-REGR | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-REAQ | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-ORRE | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-OROR | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-ORGO | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-GORE | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-GOOR | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-GOGO | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-GOGR | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-GRRE | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-GROR | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-GRGO | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-GRGR | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-AQRE | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-AQOR | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-AQGO | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-AQGR | 20 (40 μL) | 200 μL |
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| EPB41L1-BCL2A1-20-AQAQ | 20 (40 μL) | 200 μL |
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BCL2A1 Gene Summary
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: BCL2 Related Protein A1
Chromosome: CHR15: 80253231 -80263643
Locus: 15q25.1
EPB41L1 Gene Summary
Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
Gene Name: Erythrocyte Membrane Protein Band 4.1 Like 1
Chromosome: CHR20: 34700347 -34820721
Locus: 20q11.23
Gene Diseases
The EPB41L1 BCL2A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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