EPB41-PIGV Fusion FISH Probe
The EPB41-PIGV Fusion FISH Probe is used to confirm a fusion of the EPB41 and PIGV genes. The fusion of the EPB41 and PIGV genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EPB41-PIGV-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-RERE | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-REOR | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-REGO | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-REGR | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-REAQ | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-ORRE | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-OROR | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-ORGO | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-ORAQ | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-GORE | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-GOOR | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-GOGO | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-GOGR | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-GOAQ | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-GRRE | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-GROR | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-GRGO | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-GRGR | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-GRAQ | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-AQRE | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-AQOR | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-AQGO | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-AQGR | 20 (40 μL) | 200 μL |
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| EPB41-PIGV-20-AQAQ | 20 (40 μL) | 200 μL |
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EPB41 Gene Summary
The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Oct 2009]
Gene Name: Erythrocyte Membrane Protein Band 4.1
Chromosome: CHR1: 29213602 -29446558
Locus: 1p35.3
PIGV Gene Summary
This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia cognitive disability syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]
Gene Name: Phosphatidylinositol Glycan Anchor Biosynthesis Class V
Chromosome: CHR1: 27114453 -27124894
Locus: 1p36.11
Gene Diseases
The EPB41 PIGV Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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