ENO1-SNW1 Fusion FISH Probe
The ENO1-SNW1 Fusion FISH Probe is used to confirm a fusion of the ENO1 and SNW1 genes. The fusion of the ENO1 and SNW1 genes has been associated with Lung Adenocarcinoma, and Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ENO1-SNW1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-RERE | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-REOR | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-REGO | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-REGR | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-REAQ | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-ORRE | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-OROR | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-ORGO | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-GORE | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-GOOR | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-GOGO | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-GOGR | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-GRRE | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-GROR | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-GRGO | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-GRGR | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-AQRE | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-AQOR | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-AQGO | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-AQGR | 20 (40 μL) | 200 μL |
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| ENO1-SNW1-20-AQAQ | 20 (40 μL) | 200 μL |
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ENO1 Gene Summary
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]
Gene Name: Enolase 1
Chromosome: CHR1: 8921058 -8939151
Locus: 1p36.23
SNW1 Gene Summary
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Name: SNW Domain Containing 1
Chromosome: CHR14: 78183943 -78227497
Locus: 14q24.3
Gene Diseases
The ENO1 SNW1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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