ENO1-DDX27 Fusion FISH Probe
The ENO1-DDX27 Fusion FISH Probe is used to confirm a fusion of the ENO1 and DDX27 genes. The fusion of the ENO1 and DDX27 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ENO1-DDX27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-RERE | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-REOR | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-REGO | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-REGR | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-REAQ | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-ORRE | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-OROR | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-ORGO | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-ORAQ | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-GORE | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-GOOR | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-GOGO | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-GOGR | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-GOAQ | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-GRRE | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-GROR | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-GRGO | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-GRGR | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-GRAQ | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-AQRE | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-AQOR | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-AQGO | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-AQGR | 20 (40 μL) | 200 μL |
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| ENO1-DDX27-20-AQAQ | 20 (40 μL) | 200 μL |
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ENO1 Gene Summary
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]
Gene Name: Enolase 1
Chromosome: CHR1: 8921058 -8939151
Locus: 1p36.23
DDX27 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]
Gene Name: DEAD-box Helicase 27
Chromosome: CHR20: 47835831 -47860614
Locus: 20q13.13
Gene Diseases
The ENO1 DDX27 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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