EML1-ADAMDEC1 Fusion FISH Probe
The EML1-ADAMDEC1 Fusion FISH Probe is used to confirm a fusion of the EML1 and ADAMDEC1 genes. The fusion of the EML1 and ADAMDEC1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EML1-ADAMDEC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-RERE | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-REOR | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-REGO | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-REGR | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-REAQ | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-ORRE | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-OROR | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-ORGO | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-GORE | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-GOOR | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-GOGO | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-GOGR | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-GRRE | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-GROR | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-GRGO | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-GRGR | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-AQRE | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-AQOR | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-AQGO | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-AQGR | 20 (40 μL) | 200 μL |
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| EML1-ADAMDEC1-20-AQAQ | 20 (40 μL) | 200 μL |
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EML1 Gene Summary
Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Echinoderm Microtubule Associated Protein Like 1
Chromosome: CHR14: 100259744 -100408395
Locus: 14q32.2
ADAMDEC1 Gene Summary
This encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression is upregulated during dendritic cells maturation. This protein may play an important role in dendritic cell function and their interactions with germinal center T cells. [provided by RefSeq, Jul 2008]
Gene Name: ADAM Like Decysin 1
Chromosome: CHR8: 24241797 -24263526
Locus: 8p21.2
Gene Diseases
The EML1 ADAMDEC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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