ELOVL5-FAR1 Fusion FISH Probe
The ELOVL5-FAR1 Fusion FISH Probe is used to confirm a fusion of the ELOVL5 and FAR1 genes. The fusion of the ELOVL5 and FAR1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ELOVL5-FAR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-RERE | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-REOR | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-REGO | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-REGR | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-REAQ | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-ORRE | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-OROR | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-ORGO | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-GORE | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-GOOR | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-GOGO | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-GOGR | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-GRRE | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-GROR | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-GRGO | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-GRGR | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-AQRE | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-AQOR | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-AQGO | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-AQGR | 20 (40 μL) | 200 μL |
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| ELOVL5-FAR1-20-AQAQ | 20 (40 μL) | 200 μL |
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ELOVL5 Gene Summary
This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
Gene Name: ELOVL Fatty Acid Elongase 5
Chromosome: CHR6: 53132195 -53213977
Locus: 6p12.1
FAR1 Gene Summary
The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jan 2015]
Gene Name: Fatty Acyl-CoA Reductase 1
Chromosome: CHR11: 13690205 -13753893
Locus: 11p15.3
Gene Diseases
The ELOVL5 FAR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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