ELMO2-MYBL2 Fusion FISH Probe
The ELMO2-MYBL2 Fusion FISH Probe is used to confirm a fusion of the ELMO2 and MYBL2 genes. The fusion of the ELMO2 and MYBL2 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ELMO2-MYBL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-RERE | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-REOR | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-REGO | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-REGR | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-REAQ | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-ORRE | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-OROR | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-ORGO | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-GORE | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-GOOR | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-GOGO | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-GOGR | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-GRRE | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-GROR | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-GRGO | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-GRGR | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-AQRE | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-AQOR | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-AQGO | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-AQGR | 20 (40 μL) | 200 μL |
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| ELMO2-MYBL2-20-AQAQ | 20 (40 μL) | 200 μL |
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MYBL2 Gene Summary
The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
Gene Name: MYB Proto-oncogene Like 2
Chromosome: CHR20: 42295708 -42345122
Locus: 20q13.12
ELMO2 Gene Summary
The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: Engulfment And Cell Motility 2
Chromosome: CHR20: 44994689 -45035271
Locus: 20q13.12
Gene Diseases
The ELMO2 MYBL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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