ELMO1-SCIN Fusion FISH Probe
The ELMO1-SCIN Fusion FISH Probe is used to confirm a fusion of the ELMO1 and SCIN genes. The fusion of the ELMO1 and SCIN genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ELMO1-SCIN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-RERE | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-REOR | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-REGO | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-REGR | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-REAQ | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-ORRE | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-OROR | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-ORGO | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-ORAQ | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-GORE | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-GOOR | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-GOGO | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-GOGR | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-GOAQ | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-GRRE | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-GROR | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-GRGO | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-GRGR | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-GRAQ | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-AQRE | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-AQOR | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-AQGO | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-AQGR | 20 (40 μL) | 200 μL |
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| ELMO1-SCIN-20-AQAQ | 20 (40 μL) | 200 μL |
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ELMO1 Gene Summary
This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Name: Engulfment And Cell Motility 1
Chromosome: CHR7: 36892510 -37488895
Locus: 7p14.2-p14.1
SCIN Gene Summary
SCIN is a Ca(2+)-dependent actin-severing and -capping protein (Zunino et al., 2001 [PubMed 11568009]).[supplied by OMIM, May 2010]
Gene Name: Scinderin
Chromosome: CHR7: 12610202 -12693228
Locus: 7p21.3
Gene Diseases
The ELMO1 SCIN Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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