ELL2-CAST Fusion FISH Probe
The ELL2-CAST Fusion FISH Probe is used to confirm a fusion of the ELL2 and CAST genes. The fusion of the ELL2 and CAST genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ELL2-CAST-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-RERE | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-REOR | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-REGO | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-REGR | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-REAQ | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-ORRE | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-OROR | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-ORGO | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-ORAQ | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-GORE | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-GOOR | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-GOGO | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-GOGR | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-GOAQ | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-GRRE | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-GROR | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-GRGO | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-GRGR | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-GRAQ | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-AQRE | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-AQOR | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-AQGO | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-AQGR | 20 (40 μL) | 200 μL |
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| ELL2-CAST-20-AQAQ | 20 (40 μL) | 200 μL |
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CAST Gene Summary
The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Gene Name: Calpastatin
Chromosome: CHR5: 95997740 -96110385
Locus: 5q15
ELL2 Gene Summary
The Elongation Factor For RNA Polymerase II 2 (ELL2) gene is located on chr5 :95220801-95297775 at 5q15.
Gene Name: Elongation Factor For RNA Polymerase II 2
Chromosome: CHR5: 95220801 -95297775
Locus: 5q15
Gene Diseases
The ELL2 CAST Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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