ELK4-VCL Fusion FISH Probe
The ELK4-VCL Fusion FISH Probe is used to confirm a fusion of the ELK4 and VCL genes. The fusion of the ELK4 and VCL genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ELK4-VCL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-RERE | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-REOR | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-REGO | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-REGR | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-REAQ | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-ORRE | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-OROR | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-ORGO | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-ORAQ | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-GORE | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-GOOR | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-GOGO | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-GOGR | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-GOAQ | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-GRRE | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-GROR | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-GRGO | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-GRGR | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-GRAQ | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-AQRE | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-AQOR | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-AQGO | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-AQGR | 20 (40 μL) | 200 μL |
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| ELK4-VCL-20-AQAQ | 20 (40 μL) | 200 μL |
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ELK4 Gene Summary
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: ELK4, ETS Transcription Factor
Chromosome: CHR1: 205577070 -205602000
Locus: 1q32.1
VCL Gene Summary
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Vinculin
Chromosome: CHR10: 75757871 -75879914
Locus: 10q22.2
Gene Diseases
The ELK4 VCL Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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