ELK1-PCBP3 Fusion FISH Probe
The ELK1-PCBP3 Fusion FISH Probe is used to confirm a fusion of the ELK1 and PCBP3 genes. The fusion of the ELK1 and PCBP3 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ELK1-PCBP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-RERE | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-REOR | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-REGO | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-REGR | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-REAQ | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-ORRE | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-OROR | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-ORGO | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-GORE | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-GOOR | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-GOGO | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-GOGR | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-GRRE | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-GROR | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-GRGO | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-GRGR | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-AQRE | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-AQOR | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-AQGO | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-AQGR | 20 (40 μL) | 200 μL |
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| ELK1-PCBP3-20-AQAQ | 20 (40 μL) | 200 μL |
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ELK1 Gene Summary
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012]
Gene Name: ELK1, ETS Transcription Factor
Chromosome: CHRX: 47494919 -47510003
Locus: Xp11.23
PCBP3 Gene Summary
This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. The protein encoded by this gene lacks the nuclear localization signals found in other subfamily members. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017]
Gene Name: Poly(rC) Binding Protein 3
Chromosome: CHR21: 47269874 -47362368
Locus: 21q22.3
Gene Diseases
The ELK1 PCBP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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