ELAVL2-CFTR Fusion FISH Probe
The ELAVL2-CFTR Fusion FISH Probe is used to confirm a fusion of the ELAVL2 and CFTR genes. The fusion of the ELAVL2 and CFTR genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ELAVL2-CFTR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-RERE | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-REOR | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-REGO | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-REGR | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-REAQ | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-ORRE | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-OROR | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-ORGO | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-ORAQ | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-GORE | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-GOOR | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-GOGO | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-GOGR | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-GOAQ | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-GRRE | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-GROR | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-GRGO | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-GRGR | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-GRAQ | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-AQRE | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-AQOR | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-AQGO | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-AQGR | 20 (40 μL) | 200 μL |
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| ELAVL2-CFTR-20-AQAQ | 20 (40 μL) | 200 μL |
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CFTR Gene Summary
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. [provided by RefSeq, Aug 2017]
Gene Name: Cystic Fibrosis Transmembrane Conductance Regulator
Chromosome: CHR7: 117120016 -117308718
Locus: 7q31.2
ELAVL2 Gene Summary
The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Gene Name: ELAV Like RNA Binding Protein 2
Chromosome: CHR9: 23690102 -23826063
Locus: 9p21.3
Gene Diseases
The ELAVL2 CFTR Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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